Unbound MEDLINE

[Selection of management tactics in treatment of giant prolactin-secreting pituitary adenomas] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko [Zh Vopr Neirokhir Im N N Burdenko] Journal article

 
Title[Selection of management tactics in treatment of giant prolactin-secreting pituitary adenomas]
SourceZh Vopr Neirokhir Im N N Burdenko 2009 Apr-Jun; (2):23-8; discussion 28-9.
AbstractSurgical treatment of giant pituitary adenomas is one of the most complicated problems of modern neurosurgery. Before introduction of dopamine agonists surgery was the dominating therapy. Advances in modern pharmacology allowed to approach the alternative way of management of giant prolactinomas (GP). The paper focuses on comparative analysis of results of surgical and conservative treatment of 57 patients with GP. 34 of them were operated and 23 received cabergolin as primary therapy. Assessment of neurological status, visual functions, hypopituitary disorders and prolactin level was performed. Dynamics of evaluated symptoms resulting from tumor shrinking showed that primary conservative treatment of GP is more preferable than surgical.
Languagerus
Pub Type(s)English Abstract
Journal Article
PubMed ID19569545
  
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